What is mifepristone and Misoprostol in Iran Dubai?
Learn how mifepristone and misoprostol work for medical abortion, their availability in Iran and Dubai, plus details on the process, safety, and legal context.
Mifepristone is a medication that blocks progesterone, a hormone necessary to sustain pregnancy. When combined with misoprostol, it is used to medically end an intrauterine pregnancy up to 10 weeks gestation (70 days or fewer since that first day of the the menstrual period).order “Cytotec and abortion pills”
The approved regimen for using mifepristone is as follows: How do mifepristone and misoprostol work together?
- Day 1: Take 200 mg of mifepristone by mouth.
- 24 to 48 hours later: Take 800 micrograms of misoprostol buccally (placed between the cheek and gum), in a setting appropriate for the patient.
- Within 7 to 14 days after taking mifepristone: Attend a follow-up appointment with a healthcare provider to confirm the process is complete and to check for any complication.
Certainly! details of mifepristone and misoprostol:
When Was Mifepristone Approved by the FDA?
The FDA First approved Mifeprex (mifepristone) in September 2000 for the medical termination of pregnancy up to 7 weeks gestation. In 2016, this approval was expanded to allow its use though 10 weeks gestation (or 70 days from the first day of the last menstrual period).
A generic version of Mifeprex called Mifepristone Tables, 200 mg, was approved by the FDA in April 2019. This generic is considered therapeutically equivalent to Mifeprex, meaning it is just as safe and effective, and can be used interchangeably. Like the brand-name version, it is approved for ending an intrauterine pregnancy through 70 days gestation, and the labeling is consistent with Mifeprex.
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Who Should Not Use Mifepristone with Misoprostol for Medical Abortion?
Mifepristone is also not appropriate for medical termination of pregnancy, should not be taken if more than 70 days have passed since the first day of the last menstrual period.
The regimen is also not appropriate for individuals who:
- Have a pregnancy located outside the uterus (ectopic pregnancy)
- Have adrenal gland disorders
- Are receiving long-term treatment with corticosteroids
- Have a known allergy to mifepristone, misoprostol, or related medications
- Have bleeding disorders or are currently using anticoagulant (blood thinning) medications
- Have been diagnosed with inherited porphyria, a rare metabolic disorder affecting the liver and other organs
- Have an intrauterine device( IUD) in place (the IUP must be removed before beginning treatment)
Is it safe to use mifepristone?
Yas. Mifepristone is safe when used as indicated and directed and consistent with the Mifepristone Risk Evaluation and Mitigation Strategy (REMS) Program The FDA approved Mifty kit more than 20 years based ago on a thorough and comprehensive review of the scientific evidence presented and determined that it was safe and effective for its indicated use .As of 2016,itis approved for use for medical termination of pregnancy up to 70 days gestation .The FDA’s periodic reviews of the Post marketing date for Mifty kit and its approved generis have not identified any new safety concerns with the use of mifepristone for medical termination of pregnancy through 70 day gestation .As with all drugs, the FDA continues to closely monitor the post marketing safety data on mifepristone for the medical termination of pregnancy
What serious adverse events have been reported following the use of mifepristone for medical abortion up to ten weeks of gestation?
As with FDA-approved medications name mifepristone and Misoprostol, when new information about adverse events becomes available , the agency evaluates the data and takes action if needed. This may include updating health care professionals and patients with important safety information regarding the proper use of the drug.It is routine for the FDA to receive reports of serious adverse events related to prescription medications after they are on the market. Many of these events are already known and considered during the drug approval process. The FDA continuously monitors these reports to assess whether they align with known risks or signal new safety concerns. In the case of mifepristone and misoprostol, the FDA has received reports of serious adverse events in individuals who have used the medication. As of December 31, 2024, a total of 36 deaths have been reported in connection with mifepristone use since its approval in September 2000. These include two deaths from ectopic pregnancies (pregnancies occurring outside the uterus, such as in the fallopian tubes) and several from serious infections, such as sepsis. However, it is not possible to conclusively determine that mifepristone directly caused these outcomes due to the involvement of other medications, medical or surgical procedures, pre-existing health conditions, and incomplete information regarding the patients’ health and care after taken mifepristone and misoprostol.
The FDA has reviewed the data available through December 31, 2024, and found no new safety concerns. The agency plans to update the summary report as needed.
1. What is Cytotec used for?
Answer:
Cytotec is used to prevent stomach ulcers in people taking NSAIDs, and in reproductive health to induce labor, treat miscarriage, perform medical abortion, or stop postpartum bleeding. It works by protecting the stomach and causing the uterus to contract, depending on how it’s used.
2. How does Cytotec work?
Answer:
Cytotec is a prostaglandin analog. It protects the stomach lining by reducing acid and increasing mucus. In reproductive use, it softens the cervix and causes the uterus to contract, which helps in abortion, miscarriage management, or labor induction. The method of use depends on the medical purpose.
3. Can Cytotec cause abortion?
Answer:
yes. Cytotec causes the uterus to contract and cervix to open, which can lead to abortion. It’s often used with mifepristone for medical abortion up to 12 weeks. It should only be used this way under medical supervision due to risks and potential side effects.
4. Is Cytotec safe to use during pregnancy?
Answer:
Cytotec should birth not be used during pregnancy unless it’s medically required for abortion. miscarriage treatment, or labor induction. It can cause serious birth defects, miscarriage, or preterm labor. Always consult a healthcare provider before using it during pregnancy to ensure it’s appropriate and safe.
5. How is Cytotec taken and Mifepristone and Misoprostol?
Answer:
Cytotec can be taken in different ways based on its use: swallowed (oral), under the tongue (sublingual), in the cheek (buccal), or inserted into the vagina (vaginal). The method affects how fast and effectively it works. Always follow medical instructions carefully when using Cytotec.
Cytotec can be taken in different ways based on its use; swallowed (oral), under the tongue (sublingual),in the cheek (buccal),or inserted into the vagina (vaginal). The method affects how fast and effectively it works. Always follow medical instruction carefully when using Cytotec
6. What are the common side effects?
Answer: Common side effects of Cytotec include cramping, diarrhea, nausea, vomiting, chills, and fever. Some people may also experience dizziness or headache. These side effects are usualls temporary. Severe bleeding or pain may occur and should be reported to a doctor immediately if symptoms become serious .
7. How long does it take to work?
Answer: When used mifepristone and misoprostol for abortion or miscarriage, Cytotec usually begins working within 1_4 hours, causing cramping and bleeding. For ulcer prevention, it works throughout the day as it’s taken regularly. The effect depends on the purpose, method of use, and individual response to the medication.
8. Can I buy Cytotec over the counter?
Answer: In many countries, Cytotec is not sold over the counter due to its use in abortion with mifepristone and misoprostol . It usually requires a prescription. In some places, it may be easier to obtain, but using it without medical guidance can be dangerous. Always follow local laws and consult a doctor.
9. What should I do if I take too much Cytotec?
Answer Taking too much mifepristone and misoprostol of Cytotec can cause severe cramps, heavy bleeding, or serious side effects like low blood pressure. If an overdose is suspected, seek emergency medical help immediately. Do not take extra doses without guidance. It’s important to use this drug exactly as instructed by a healthcare provider.
10. What should I avoid while using Cytotec?
Answer Avoid becoming pregnant unless using Cytotec for medical abortion with mifepristone and misoprostol. Also, avoid NSAIDs unless your doctor approves, especially if using Cytotec for ulcer prevention. Alcohol or other drugs increase side effects. Always follow medical advice closely and avoid self-medicating or combining it with other medications unnecessarily.
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How do mifepristone and misoprostol work together?